Hester was named NAIA Third-Team All-American in 2012 after averaging 15.5 points and 8.6 rebounds for the University of Mobile.
In 2012, Hester joined Turun NMKY of the Finnish First Division.
In 2014, Hester played for Real Club of Lima in the Liga de Basket de Lima, helping them win the Peruvian championship in July that year.
He played for CB Tarragona during the 2014–15 LEB Plata season, averaging 13.4 points and 7.6 rebounds. In September 2014, he helped the club to victory in the LEB Catalan basketball league and was named the finals MVP.
In August 2016, Hester signed with Tindastóll of the Icelandic Úrvalsdeild karla. A month later, Tindastóll released Hester to sign Mamadou Samb. In November, Tindastóll brought Hester back as a part of a major roster overhaul where they fired head coach José Maria Costa and released Samb and Pape Seck. For the season he averaged 23.5 points and 10.7 rebounds in 32.0 minutes per game. Tindastóll finished third in the league but despite home court advantage, it lost to Keflavík in the first round of the playoffs.
In June 2017, Hester resigned with Tindastóll for the 2017–2018 season. In November 2017, Hester injured his ankle badly and was initially thought to have broken it. Further tests revealed that the ankle was unbroken and that recovery time would be in weeks, not months.
On January 13, 2018, Hester helped Tindastóll to its first major title when it won the Icelandic Basketball Cup.
For the season, Hester averaged 20.6 points and 8.7 rebounds in 25.3 minutes per game, helping Tindastóll to a 16-6 record and the third seed in the playoffs.
In the playoffs, Tindastóll swept Grindavík, 3-0, in the first round, advancing to the semi-finals against ÍR. In the fifth game of the semi-finals on April 13, 2018, Hester injured his ankle. Despite the injury, Tindastóll prevailed in the game and advanced to the Úrvalsdeild finals Although hobbled, Hester played in the first game of the finals series against four-time defending champions of KR. There he injured his other ankle after trying to block a shot from Brynjar Þór Björnsson, resulting in him missing game two of the series. Without him, Tindastóll staged a spirited performance, blowing out KR on their own homecourt, 98-70, and tying the series at one game apiece. After the season he was named the Úrvalsdeild Karla Foreign Player of the Year.
In December 2018, Hester signed with Starwings Basel of the Swiss Basketball League. In 14 games, he averaged 19.9 points and 9.6 rebounds per game.
Hester spent the 2019–220 season with Bàsquet Girona in LEB Plata where he averaged 13.1 points and 8.3 rebounds in 25 games.
Antonio Hester averaged 13.1 points, 8.3 rebounds and 1.8 assists per game, playing 25 games with Basquet Girona, during the 2019-2020 Spain – LEB Silver regular-season. He set his season-high with 27 points in 22 minutes against Benicarlo on October 02, 2019. He grabbed a season-high 13 rebounds in 30 minutes against CBA Gran Canaria on October 13, 2019. He dished a season-high 5 assists in 31 minutes against Benicarlo on December 15, 2019.
He scored in double figures 19 times in 25 games. He had 20 points or more 4 times. He recorded 8 double-doubles.
Awards, titles and accomplishments
NAIA Third-Team All-American: 2012
LEB Catalan Finals MVP: 2014
Úrvalsdeild Karla Foreign Player of the Year: 2018
Peruvian League: 2014
LEB Catalan basketball league: 2014
Icelandic Basketball Cup: 2018